polyclonal antibody α hsf Search Results


hsf1(ser326) polyclonal antibody  (Bioss)
93
Bioss hsf1(ser326) polyclonal antibody
Hsf1(Ser326) Polyclonal Antibody, supplied by Bioss, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hsf1(ser326) polyclonal antibody/product/Bioss
Average 93 stars, based on 1 article reviews
hsf1(ser326) polyclonal antibody - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
rabbit polyclonal antibody against hsf1  (Signalway Antibody)
90
Signalway Antibody rabbit polyclonal antibody against hsf1
Differential expression of proteins and signaling pathways in the sensitive and non-sensitive groups of the chemoradiotherapy subcohort (A) The pathway enrichment results are shown. (B) The proportion of patients treated with FOLFOX plus radiotherapy in the chemoradiotherapy subcohort and the consistent pathway enrichment in S and NS groups. (C) Differential expression of proteins involved in the consistent featured pathways. (D) The interaction network of proteins involved in the one-carbon metabolism pathway. (E) Differential expression of TFs in the FOLFOX plus radiotherapy subcohort. (F) Differential expression of <t>HSF1</t> in the S and NS groups in the GSE68204 dataset (S, N = 18; NS, N = 17). Boxplots show median (central line), upper and lower quartiles (box limits), and 1.5 × interquartile range (whiskers). (G) Spearman correlation of HSF1 and one-carbon metabolism ssGSEA score. (H) ROC curve of the combined predictive model signatures. (I) Differential expression of the S/NS-sig quantified using the PRM approach in an independent cohort (two-sided Wilcoxon rank-sum test; S, N = 21; NS, N = 19). (J) Qualification of HSF1 stained by IHC in representative examples. The scale bar indicates 100 μm. Data are analyzed using two-sided Student’s t test and shown as mean ± SD (n = 3 independent experiments). (K) Schematic illustration indicating the potential regulation HSF1 in response to chemoradiotherapy.
Rabbit Polyclonal Antibody Against Hsf1, supplied by Signalway Antibody, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit polyclonal antibody against hsf1/product/Signalway Antibody
Average 90 stars, based on 1 article reviews
rabbit polyclonal antibody against hsf1 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

Image Search Results


Differential expression of proteins and signaling pathways in the sensitive and non-sensitive groups of the chemoradiotherapy subcohort (A) The pathway enrichment results are shown. (B) The proportion of patients treated with FOLFOX plus radiotherapy in the chemoradiotherapy subcohort and the consistent pathway enrichment in S and NS groups. (C) Differential expression of proteins involved in the consistent featured pathways. (D) The interaction network of proteins involved in the one-carbon metabolism pathway. (E) Differential expression of TFs in the FOLFOX plus radiotherapy subcohort. (F) Differential expression of HSF1 in the S and NS groups in the GSE68204 dataset (S, N = 18; NS, N = 17). Boxplots show median (central line), upper and lower quartiles (box limits), and 1.5 × interquartile range (whiskers). (G) Spearman correlation of HSF1 and one-carbon metabolism ssGSEA score. (H) ROC curve of the combined predictive model signatures. (I) Differential expression of the S/NS-sig quantified using the PRM approach in an independent cohort (two-sided Wilcoxon rank-sum test; S, N = 21; NS, N = 19). (J) Qualification of HSF1 stained by IHC in representative examples. The scale bar indicates 100 μm. Data are analyzed using two-sided Student’s t test and shown as mean ± SD (n = 3 independent experiments). (K) Schematic illustration indicating the potential regulation HSF1 in response to chemoradiotherapy.

Journal: Cell Reports Medicine

Article Title: Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies

doi: 10.1016/j.xcrm.2023.101311

Figure Lengend Snippet: Differential expression of proteins and signaling pathways in the sensitive and non-sensitive groups of the chemoradiotherapy subcohort (A) The pathway enrichment results are shown. (B) The proportion of patients treated with FOLFOX plus radiotherapy in the chemoradiotherapy subcohort and the consistent pathway enrichment in S and NS groups. (C) Differential expression of proteins involved in the consistent featured pathways. (D) The interaction network of proteins involved in the one-carbon metabolism pathway. (E) Differential expression of TFs in the FOLFOX plus radiotherapy subcohort. (F) Differential expression of HSF1 in the S and NS groups in the GSE68204 dataset (S, N = 18; NS, N = 17). Boxplots show median (central line), upper and lower quartiles (box limits), and 1.5 × interquartile range (whiskers). (G) Spearman correlation of HSF1 and one-carbon metabolism ssGSEA score. (H) ROC curve of the combined predictive model signatures. (I) Differential expression of the S/NS-sig quantified using the PRM approach in an independent cohort (two-sided Wilcoxon rank-sum test; S, N = 21; NS, N = 19). (J) Qualification of HSF1 stained by IHC in representative examples. The scale bar indicates 100 μm. Data are analyzed using two-sided Student’s t test and shown as mean ± SD (n = 3 independent experiments). (K) Schematic illustration indicating the potential regulation HSF1 in response to chemoradiotherapy.

Article Snippet: A standard immunohistochemistry (IHC) protocol was followed to stain the tumor tissue samples using the rabbit polyclonal antibody against, the rabbit polyclonal antibody against HSF1 (Signalway Antibody, catalog No: 41037-1), and the rabbit polyclonal antibody against HDAC6 (Signalway Antibody, catalog No: 40999-1).

Techniques: Expressing, Staining

Effect of HSF1 expression on response to radiotherapy in CRC cell lines (A) Effect of HSF1 overexpression on proliferation in CRC cells (n = 3 independent experiments, two-sided Student’s t test, mean ± SD). (B) CRC cells were exposed to increasing doses of ionizing radiation (0, 2, 4, and 8 Gy), and surviving cells were quantified by CCK8 (n = 6 independent experiments, two-sided Student’s t test, mean ± SD). (C) Representative γH2AX foci present in HSF1-OE and control cells. Differential proteins and KEGG pathway alteration of the pre-irradiation (D) and post-irradiation (E) HSF1-OE group and HSF1-KD group. (F) Differential proteins and KEGG pathway alteration of post-irradiation 1, 2, and 12 h compared with pre-irradiation HSF1-OE group. (G and H) Boxplot showing the cell cycle and autophagy ssGSEA scores of the HSF1-OE/KD groups pre-irradiation and 1, 2, and 12 h post-irradiation (ANOVA, n = 3 biologically independent samples in each cell line). Boxplots show median (central line), upper and lower quartiles (box limits), and 1.5 × interquartile range (whiskers). (I) GSEA of autophagy of the HSF1-KD group 1, 2, and 12 h post-irradiation compared with the HSF1-OE group. (J) Correlation of HSF1 and ssGSEA scores of autophagy and cell cycle. (K) Differential expression of key proteins involved in these pathways 1, 2, and 12 h post-irradiation in the HSF1-OE/KD groups (left). Pearson’s correlation of these proteins with radiation dose (right).

Journal: Cell Reports Medicine

Article Title: Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies

doi: 10.1016/j.xcrm.2023.101311

Figure Lengend Snippet: Effect of HSF1 expression on response to radiotherapy in CRC cell lines (A) Effect of HSF1 overexpression on proliferation in CRC cells (n = 3 independent experiments, two-sided Student’s t test, mean ± SD). (B) CRC cells were exposed to increasing doses of ionizing radiation (0, 2, 4, and 8 Gy), and surviving cells were quantified by CCK8 (n = 6 independent experiments, two-sided Student’s t test, mean ± SD). (C) Representative γH2AX foci present in HSF1-OE and control cells. Differential proteins and KEGG pathway alteration of the pre-irradiation (D) and post-irradiation (E) HSF1-OE group and HSF1-KD group. (F) Differential proteins and KEGG pathway alteration of post-irradiation 1, 2, and 12 h compared with pre-irradiation HSF1-OE group. (G and H) Boxplot showing the cell cycle and autophagy ssGSEA scores of the HSF1-OE/KD groups pre-irradiation and 1, 2, and 12 h post-irradiation (ANOVA, n = 3 biologically independent samples in each cell line). Boxplots show median (central line), upper and lower quartiles (box limits), and 1.5 × interquartile range (whiskers). (I) GSEA of autophagy of the HSF1-KD group 1, 2, and 12 h post-irradiation compared with the HSF1-OE group. (J) Correlation of HSF1 and ssGSEA scores of autophagy and cell cycle. (K) Differential expression of key proteins involved in these pathways 1, 2, and 12 h post-irradiation in the HSF1-OE/KD groups (left). Pearson’s correlation of these proteins with radiation dose (right).

Article Snippet: A standard immunohistochemistry (IHC) protocol was followed to stain the tumor tissue samples using the rabbit polyclonal antibody against, the rabbit polyclonal antibody against HSF1 (Signalway Antibody, catalog No: 41037-1), and the rabbit polyclonal antibody against HDAC6 (Signalway Antibody, catalog No: 40999-1).

Techniques: Expressing, Over Expression, Irradiation

Journal: Cell Reports Medicine

Article Title: Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies

doi: 10.1016/j.xcrm.2023.101311

Figure Lengend Snippet:

Article Snippet: A standard immunohistochemistry (IHC) protocol was followed to stain the tumor tissue samples using the rabbit polyclonal antibody against, the rabbit polyclonal antibody against HSF1 (Signalway Antibody, catalog No: 41037-1), and the rabbit polyclonal antibody against HDAC6 (Signalway Antibody, catalog No: 40999-1).

Techniques: Formalin-fixed Paraffin-Embedded, Recombinant, Mass Spectrometry, Plasmid Preparation, CCK-8 Assay, Expressing, Software